Duct material now changes the answer. Galvanized, duct board and flexible duct each carry their own ASHRAE roughness, and flex needs a full standard size more than metal at the same airflow. Size a flex run as if it were metal and it always goes in over its design friction rate, by up to double. New Check tab for the duct that's already there: type in a round diameter or a width and height and read back its velocity, its friction rate, and the airflow it will actually carry, with a verdict against whichever limit binds first. Also: a friction rate you type in now survives switching between supply and return. Manual D designs a whole system to one rate, so the per-service defaults no longer overwrite a number you worked out yourself.